10 Best Hand Sanitizers 2025 in the United States

The PURELL Advanced Hand Sanitizer Refreshing Gel is a strong contender in the hand sanitizer category, especially for high-traffic environments such as schools and offices. With 70% ethyl alcohol, it effectively kills 99.99% of germs, making it a reliable option for maintaining hygiene when soap and water aren't accessible. One of its significant strengths is the mild formula infused with moisturizers, which helps keep hands feeling soft even after frequent use. This is particularly beneficial for those who sanitize their hands often, as many sanitizers can be harsh and drying. Moreover, it is free from triclosan, parabens, phthalates, and preservatives, which is a plus for users who are conscious about the ingredients in their skincare products.

The clean scent adds to the experience, making it pleasant to use without being overwhelming. The 12 fl oz pump bottles are convenient for placement in areas where quick access to hand sanitization is needed, and since they come in a pack of 12, they offer good value for settings that require multiple dispensers.

The PURELL Advanced Hand Sanitizer Gel Infused with Essential Oils offers a practical and effective way to maintain hand hygiene. With an alcohol content of 70% ethyl alcohol, it is highly effective in killing 99.99% of common germs. The product comes in a convenient travel size, making it easy to carry in a purse, gym bag, or briefcase.

The gel formulation is gentle on the skin, free from parabens, phthalates, and preservatives, ensuring it does not cause dryness or irritation with frequent use. Plus, the inclusion of essential oils provides a pleasant scent, with options like Mandarin, Lavender, and Mint, adding a refreshing touch to the sanitizing experience.

Each box contains 12 one-ounce bottles, making it a cost-effective choice for those who need to sanitize their hands regularly on the go. Ideal for people who need a reliable, portable hand sanitizer that is both effective and gentle on the skin.

PURELL Advanced Hand Sanitizer Naturals stands out in the realm of hand sanitizers for its commitment to using plant-based alcohol. With an alcohol content of 70%, it offers a high level of germ-killing effectiveness, boasting 2X sanitizing strength compared to many other brands. This means you can achieve the same level of cleanliness with less product, which is a great advantage for frequent use. The 8 fl oz pump bottles are convenient for home or office settings, making it easy to keep your hands clean when soap and water aren't available.

One of the significant strengths of this product is its formulation. It's EcoLogo certified and includes essential oils and natural skin conditioners, making it a more skin-friendly choice. It avoids harsh chemicals like triclosan and parabens, which is a plus for those looking for cleaner products. Additionally, the citrus scent can make the experience more pleasant compared to the often overpowering smell of traditional alcohol-based sanitizers.

There are a few drawbacks to consider. While the scent may be appealing to some, those sensitive to fragrances might find it too strong. The pump bottle size, while practical for stationary use, might not be the most portable option for on-the-go sanitization. If you're looking for something to carry in your bag or pocket, this pack of 4 large bottles may feel bulky. Lastly, while the plant-based ingredients are a plus, some might question the efficacy in comparison to other hand sanitizers that utilize more traditional formulations.