10 Best Bed Bug Treatments 2025 in the United States

Ortho Home Defense Max Bed Bug, Flea and Tick Killer is a spray treatment designed to target and eliminate bed bugs, their eggs, fleas, and ticks. The product is particularly effective against even resistant bed bugs, making it a strong option for persistent infestations. It comes with a Comfort Wand, which allows for precise application in hard-to-reach areas such as bed frames, baseboards, and mattress seams. This ease of use is a major advantage, especially for those who may not have much experience with pest control products.

The spray is part of a larger system offered by Ortho, which suggests using additional products for comprehensive results, potentially increasing effectiveness when used as directed. Safety-wise, as with many chemical treatments, caution is required to avoid contact with skin and inhalation, and it is important to follow the manufacturer's guidelines closely to ensure safe usage around children and pets. The residual effect is not extensively highlighted, so it may require reapplication to maintain effectiveness over time.

Cost-wise, the product is reasonably priced for a gallon of treatment, and its high customer ratings (4.4 out of 5 stars from over 28,000 reviews) suggest general satisfaction among users. However, the need for complementary products in the Ortho system could increase the total cost for comprehensive treatment. In summary, Ortho Home Defense Max is a user-friendly, effective solution for bed bug infestations, but users should be mindful of safety precautions and the potential need for additional products for best results.

The Ortho Home Defense Max Bed Bug Killer is a spray designed to tackle bed bugs, including tough pyrethroid-resistant ones and their eggs, making it a strong choice for persistent infestations. It also kills other pests like fleas and ticks, adding versatility. The spray is easy to use as a spot treatment around bed frames, carpets, and other common bed bug hiding places. One of its notable advantages is the residual effect; it continues to kill bed bugs for up to 16 weeks on hard surfaces, which helps reduce the need for frequent reapplication. It is unscented, which is a plus if you prefer a product without strong odors.

While it is effective on non-porous surfaces, its effectiveness might be less on fabrics or porous materials, so combining it with other steps or products (like traps and powders from the same brand) can improve results. Safety-wise, as with most insecticides, you should follow instructions carefully to avoid direct contact or inhalation. The cost is reasonable, especially given that you get two 18 oz. sprays in the pack, making it a budget-friendly option for many households.

This product suits homeowners looking for a straightforward, effective spray with lasting protection against bed bugs and other pests, especially in mild to moderate cases. Since it is mainly a spot treatment, it might not be enough for severe infestations without an integrated approach.