10 Best Herbicides For Centipede Grass 2026 in the United States

Prime Source Celsius WG is a post-emergent herbicide designed to target both broadleaf and grassy weeds, making it suitable for gardeners dealing with common lawn weeds. It comes in an easy-to-use mix packet, eliminating the need for measuring and simplifying application.

While the product is labeled safe for St. Augustine grass, its safety for centipede grass is not explicitly stated, so caution is advised for use on centipede lawns, and testing a small area first is recommended. The product contains a combination of active ingredients known for professional-quality results, effectively controlling dandelions and other tough weeds.

The granule form in a liquid mix ensures even application, and since it is post-emergent, it targets existing weeds rather than preventing weed seeds from growing. This product offers a reliable solution for controlling broadleaf and grassy weeds with a straightforward mixing process, but verifying compatibility with your specific lawn type is important before full use.

Ortho WeedClear Weed Killer for Lawns is a selective herbicide that effectively targets over 250 common weeds, including dandelions and clover, making it a versatile choice for lawn care. Its formula is designed to kill weeds down to the root without harming your grass, provided it is used as directed, which is critical for maintaining centipede grass.

The product is pre-mixed and comes in a ready-to-spray format, which simplifies the application process; you just need to connect it to your garden hose and spray. This ease of use is ideal for homeowners who prefer a straightforward weed control method. Additionally, it is rainproof within an hour, allowing for quick re-entry of people and pets into treated areas after the spray has dried.

While it claims to be safe for lawns when used correctly, it's important to follow the directions carefully to avoid any potential harm to centipede grass. The product's effectiveness may vary, and it may not be suitable for all types of lawns or weeds not listed on the product label. Therefore, users should check the complete weed list on the label to ensure it targets the specific weeds present in their lawn. Ortho WeedClear offers a reliable solution for weed control in lawns with centipede grass, combining ease of use and effective weed elimination, but requires careful application to ensure optimal results.

The Andersons Barricade Professional-Grade Granular Pre-Emergent Weed Control is a solid choice for those looking to prevent weeds in their centipede grass lawns. Designed as a pre-emergent herbicide, it effectively stops a variety of grassy and broadleaf weeds before they sprout, including common nuisances like crabgrass and goosegrass. This product is not intended for eliminating existing weeds, so it's best used as a preventative measure in early spring and fall.

With a coverage of up to 5,800 square feet and an active ingredient concentration of 0.48% prodiamine, it offers professional-grade weed control. The DG Pro formulation ensures even distribution and superior performance by allowing more particles per square inch. Applying it in granular form is straightforward, and it’s safe for use on centipede grass, making it suitable for homeowners and lawn care professionals alike.

However, those dealing with established weeds will need a different solution, as this product is only effective as a pre-emergent. Additionally, the 18-pound weight may be cumbersome for some users, and careful application is needed to avoid overuse. Made in the USA, this product is a trusted option in the lawn care market.